1. Marshawn Lynch vs. Min – Beast mode will roll for 125 yards and 2 TDs.

2. Jamaal Charles vs. Den – He’ll light up the Broncos D on SNF.

3. Reggie Bush vs. Pit – Bush will top 125 total yards and find the end zone.

4. Frank Gore vs. NO – Expect the 49ers to rely heavily on the run game this week.

Not far behind

LeSean McCoy vs. Was – Expect a repeat of Week 1.

Adrian Peterson vs. Sea – He’ll find it tough sledding in Seattle but All Day is always a threat to break one.

Alfred Morris vs. Phi – Morris will hit the 100 yards mark again and find the end zone.

Rounding things out

Chris Johnson vs. Ind – There will be room to run vs. the Colts on Thursday.

Andre Brown vs. GB – The Giants have recommitted to the run game.

DeAngelo Williams vs. NE – Williams will top 80 yards with a score.

Knowshon Moreno vs. KC – The passing game will open up holes for Moreno. He’ll hit 75 yards with a TD.

Giovani Bernard vs. Cle – The big play rookie will be a threat as a receiver as well as runner.

Darren Sproles vs. SF – He’ll make a major impact in the passing game, primarily on screens.

Ben Tate vs. Oak – The Raiders just got run over by the Giants.

Le’veon Bell vs. Det – He’ll catch 4-5 balls in addition to his rushing yards.

Danny Woodhead vs. Mia – The Chargers will continue to give him No. 1 touches.

Eddie Lacy vs. NYG – The Giants have been tough on opposing RBs so this lowers him a bit.

Potential Bust – Beware

Stevan Ridley vs. Car – The Panthers front 7 is extremely physical and good against the run.

1. LeSean McCoy vs. NYG – McCoy ALWAYS torches the Giants.

2. Marshawn Lynch vs. Ind – Down three OL men? No problem. Beast Mode just keeps pounding away. He will top 100 yards with 2 TDs.

3. Frank Gore vs. Hou – The 49ers got wise and played power football vs. the Rams. They’ll do it again right back.

4. Jamaal Charles vs. Ten – Ten will have trouble with the shifty, speedy back who is posting solid fantasy points weekly.

Not far behind

Reggie Bush vs. GB – Detroit’s newest big play threat topped 100 yards with a TD vs. the Bears. Bush will give the Packers D fits.

Matt Forte vs. NO – Forte will have plenty of success against the Saints.

Chris Johnson vs. KC – Tennessee will rely on Johnson this week. He’ll respond with 100 yards and a TD.

Rounding things out

Knowshon Moreno vs. Dal – He’s the ultimate beneficiary of the Broncos vaunted passing game.

DeAngelo Williams vs. Arz – Look for Williams to continue his impressive start in Arizona.

Giovani Bernard vs. NE – The Pats are missing DT Vince Wolfork which leaves a gaping hole in the middle of the Pats D.

Arian Foster vs. SF – Look for Foster to be active in the running as well as passing game at the Stick.

David Wilson vs. Phi – He’s a flex play at this point but could get going against the Eagles.

Eddie Lacy vs. Det- Lacy should be healed from his earlier concussion.

Danny Woodhead vs. Oak – He may have supplanted Matthews as the top back in SD. Woodhead is a threat as a receiver and runner.

Darren McFadden vs. SD – His hamstring injury is apparently minor.

DeMarco Murray vs. Den – He could fare better as a receiver in the short passing game vs. the Broncos.

Steven Jackson vs. NYJ – Check his status before putting back into your lineup. This is a decent match-up if so.

Stevan Ridley vs. Cin – He’s been a disappointment thus far, but having Gronk and Amendola back could provide the boost he needs.

Potential Bust – Beware

CJ Spiller vs. Cle – Spiller is slated to play on Thursday but it’s best to look elsewhere. No one runs on the Browns.