1. Marshawn Lynch vs. Min – Beast mode will roll for 125 yards and 2 TDs.
2. Jamaal Charles vs. Den – He’ll light up the Broncos D on SNF.
3. Reggie Bush vs. Pit – Bush will top 125 total yards and find the end zone.
4. Frank Gore vs. NO – Expect the 49ers to rely heavily on the run game this week.
Not far behind
LeSean McCoy vs. Was – Expect a repeat of Week 1.
Adrian Peterson vs. Sea – He’ll find it tough sledding in Seattle but All Day is always a threat to break one.
Alfred Morris vs. Phi – Morris will hit the 100 yards mark again and find the end zone.
Rounding things out
Chris Johnson vs. Ind – There will be room to run vs. the Colts on Thursday.
Andre Brown vs. GB – The Giants have recommitted to the run game.
DeAngelo Williams vs. NE – Williams will top 80 yards with a score.
Knowshon Moreno vs. KC – The passing game will open up holes for Moreno. He’ll hit 75 yards with a TD.
Giovani Bernard vs. Cle – The big play rookie will be a threat as a receiver as well as runner.
Darren Sproles vs. SF – He’ll make a major impact in the passing game, primarily on screens.
Ben Tate vs. Oak – The Raiders just got run over by the Giants.
Le’veon Bell vs. Det – He’ll catch 4-5 balls in addition to his rushing yards.
Danny Woodhead vs. Mia – The Chargers will continue to give him No. 1 touches.
Eddie Lacy vs. NYG – The Giants have been tough on opposing RBs so this lowers him a bit.
Potential Bust – Beware
Stevan Ridley vs. Car – The Panthers front 7 is extremely physical and good against the run.